#45 Crazy Experiment proves how we became human ...

Recent Experiments on Nova1, Foxp2, and TKTL1 show that human evolution heavily favoured brain efficiency over size. And we trace back where all these mutations came from and what it means.


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Darnell et al., Nature Communications (2023) – Study identifying human-specific NOVA1 variant and its effects.
Tajima et al., Nature Communications (2023) – Experiments inserting human NOVA1 into mice and observing vocalization changes.
Pinson et al., Science (2022) – Discovery of TKTL1 mutation increasing neuron production in modern humans vs. Neanderthals​
neurosciencenews.com
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neurosciencenews.com
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Schreiweis et al., PNAS (2014) – Study on humanized FOXP2 in mice, showing accelerated habit learning and altered dopamine signaling​
news.mit.edu
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Various historical and anthropological sources on human evolution and civilization.



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Scientist test 3 ancient Intelligence DNA. And all of them point to Africa as the source of Intelligence for humans.

TKTL1, responsible for neurone explosion / high concentration. Present in early hominids in Africa, but not Neanderthal

NOVA1, Responsible for speech, planning and curiosity. Present in Human in Africa before they left, but not present in Neanderthal.

Foxp2, Present in Neanderthal, but the neanderthal version has been shown to cause lack of curiosity and laziness.

So no, Neanderthal wasn't as smart as your cousin next door. It couldn't talk and couldn't think like humans.